Device Use Patterns and Clinical Outcome of Implantable Cardioverter Defibrillator Patients with Moderate and Severe Impairment of Left Ventricular Function

作者: DAVENDRA MEHTA , SANJEEV SAKSENA , RYSZARD B. KROL , THAMPI JOHN , AMARKANTH SAXENA

DOI: 10.1111/J.1540-8159.1993.TB01558.X

关键词: Device useMedicineInternal medicineVentricular functionDefibrillationEjection fractionIncidence (epidemiology)CardiologyCoronary artery diseaseImplantable cardioverter-defibrillatorSudden deathIntensive care medicine

摘要: The beneficial effects of implanted cardioverter defibrillator (ICD) therapy in patients with malignant ventricular tachyarrhythmias and variable degrees left (LV) dysfunction are debated. ICD use patient survival were examined 128 arrhythmias moderate or severe LV dys function. Group I included 64 (LV ejection fraction > 30%) group H, fracfion ≤ 30%). Follow-up period ranged from 1 to 78 months. two groups similar age, incidence coronary artery disease presenting arrhythmia. mean was 44%± 8% II 22%± 5% (P < 0.0001). At 4 years follow-up, 66% 62% = NS) had activation for presumed tachyarrhythmia. Survival calculated using actuarial analysis. Arrhythmic sudden death mortality at follow-up 4% 7% NS). Cardiac I, 0.05), 12% (fP 0,01), 15% 0.01), 0.01) 1, 2, 3, 4, respectively. For II, cardiac 27%, 36%, 41%, 41% majority deaths both observed the first 2 follow-up. However, groups, comparable who did (users) not (nonusers) experience appropriate shocks. Thus, long-term is dysfunction. higher irrespective device use. clinical outcome users non can be related elimination arrhythmic mortality. Long-term recipients remains substantial even

参考文章(19)
Richard N. Fogoros, James J. Elson, Christopher A. Bonnet, Susan B. Fiedler, John A. Burkholder, Efficacy of the automatic implantable cardioverter-defibrillator in prolonging survival in patients with severe underlying cardiac disease Journal of the American College of Cardiology. ,vol. 16, pp. 381- 386 ,(1990) , 10.1016/0735-1097(90)90590-L
Joseph A. Franciosa, Mary Wilen, Susan Ziesche, Jay N. Cohn, Survival in men with severe chronic left ventricular failure due to either coronary heart disease or idiopathic dilated cardiomyopathy American Journal of Cardiology. ,vol. 51, pp. 831- 836 ,(1983) , 10.1016/S0002-9149(83)80141-6
E. L. Kaplan, Paul Meier, Nonparametric Estimation from Incomplete Observations Springer Series in Statistics. ,vol. 53, pp. 319- 337 ,(1992) , 10.1007/978-1-4612-4380-9_25
Robert J. Myerburg, Richard M. Luceri, Richard Thurer, Deborah K. Cooper, Liaqat Zaman, Alberto Interian, Pedro Fernandez, Marilyn Cox, Frances Glicksman, Agustin Castellanos, Time to first shock and clinical outcome in patients receiving an automatic implantable cardioverter-defibrillator. Journal of the American College of Cardiology. ,vol. 14, pp. 508- 514 ,(1989) , 10.1016/0735-1097(89)90209-X
KATHI AXTELL, PATRICK TCHOU, MASOOD AKHTAR, Survival in patients with depressed left ventricular function treated by implantable cardioverter defibrillator. Pacing and Clinical Electrophysiology. ,vol. 14, pp. 291- 296 ,(1991) , 10.1111/J.1540-8159.1991.TB05109.X
Richard J. Thurer, Richard M. Luceri, Hooshang Bolooki, Automatic Implantable Cardioverter-Defibrillator: Techniques of Implantation and Results The Annals of Thoracic Surgery. ,vol. 42, pp. 143- 147 ,(1986) , 10.1016/S0003-4975(10)60507-3
L T Sheffield, Upsloping ST segments. Easy to measure, hard to agree upon. Circulation. ,vol. 84, pp. 426- 428 ,(1991) , 10.1161/01.CIR.84.1.426