Homo crystallographicus--quo vadis?

作者: Gerard J Kleywegt , T.Alwyn Jones

DOI: 10.1016/S0969-2126(02)00743-8

关键词: Constant (mathematics)CrystallographyStatistical physicsModel validationFunction (mathematics)Resolution (electron density)Reliability (statistics)Quality (physics)ChemistryRamachandran plot

摘要: As macromolecular crystal structures are determined and refined in an increasingly automated fashion, careful assessment of the reliability quality resulting models becomes important. Here, we analyze various issues related to deposited between 1991 2000. We find that average resolution at which these is essentially constant. In line with this observation, as measured by Ramachandran analysis does not improve a function time. On other hand, observed decrease discrepancy free conventional R values suggests fit model data improving. Finally, present surprising correlation tendency crystallographers deposit their experimental models.

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