Oxygen Transport during Exercise at Altitude

作者: Paolo Cerretelli

DOI: 10.1007/978-1-4757-1721-1_25

关键词: Partial pressureAcute hypoxiaChronic hypoxiaMaterials scienceProlonged exposureArterial oxygenOxygen transportSaturation (chemistry)Analytical chemistry

摘要: Maximal oxygen consumption \( ({\dot V_{{O_2}}}\max ) \) undergoes a progressive reduction in hypoxia both acute and chronic as appears from Fig. 1 where data various authors are summarized. Such decrease, for pressure drop of half an atmosphere (corresponding to altitude about 5500 meters) ranges between 30% 45%, independent the degree acclimatization ethnic characteristics sub.iects. Common factors known change {\dot opposite directions In are: 1) The decreased arterial O 2 saturation (%HbO2) due {P_{{I_{{O_2}}}}} possibly impairment diffusion property lung. The carbon dioxide partial pressures P{a_{{O_2}}}{\kern 1pt} and{\kern P{a_{C{O_2}}} resident highlanders well acclimatized lowlanders plotted function 2, along with corresponding HbO2 values (HbO2). At barometric 380 torr (5500 m) %HbO2 drops 80%. 2) The increased Blood hemoglobin (Hb) concentration. Hb concentration, after prolonged exposure m, may attain 130–140% sea level control value.

参考文章(22)
Kåre Rodahl, Per-Olof Åstrand, Textbook of Work Physiology ,(1970)
M. Samaja, A. Veicsteinas, P. Cerretelli, Oxygen affinity of blood in altitude Sherpas Journal of Applied Physiology. ,vol. 47, pp. 337- 341 ,(1979) , 10.1152/JAPPL.1979.47.2.337
J A Vogel, L H Hartley, J C Cruz, Cardiac output during exercise in altitude natives at sea level and high altitude. Journal of Applied Physiology. ,vol. 36, pp. 173- 176 ,(1974) , 10.1152/JAPPL.1974.36.2.173
P. Cerretelli, J.C. Cruz, L.E. Farhi, H. Rahn, Determination of mixed venous O2 and CO2 tensions and cardiac output by a rebreathing method Respiration Physiology. ,vol. 1, pp. 258- 264 ,(1966) , 10.1016/0034-5687(66)90045-4
Dorothy S Dittmer, Philip L Altman, Biology data book ,(1964)
MELVIN H. WILLIAMS, A. RAY GOODWIN, ROBIN PERKINS, JERALD BOCRIE, Effect of blood reinjection upon endurance capacity and heart rate. Medicine and science in sports. ,vol. 5, pp. 181- ,(1973) , 10.1249/00005768-197323000-00016
R. Margaria, E. Camporesi, P. Aghemo, G. Sassi, The effect of O 2 breathing on maximal aerobic power. Pflügers Archiv: European Journal of Physiology. ,vol. 336, pp. 225- 235 ,(1972) , 10.1007/BF00590047
L. Fagraeus, J. Karlsson, D. Linnarsson, B. Saltin, Oxygen uptake during maximal work at lowered and raised ambient air pressures. Acta Physiologica Scandinavica. ,vol. 87, pp. 411- 421 ,(1973) , 10.1111/J.1748-1716.1973.TB05405.X
David VB James, Leigh E Sandals, Dan M Wood, Andrew M Jones, Pulmonary gas exchange International review of physiology. ,vol. 14, pp. 83- 106 ,(1977) , 10.4324/9780203966846-24
Paolo Cerretelli, Rodolfo Margaria, Maximum oxygen consumption at altitude Internationale Zeitschrift f�r Angewandte Physiologie Einschliesslich Arbeitsphysiologie. ,vol. 18, pp. 460- 464 ,(1961) , 10.1007/BF00699458