Advances in clinical trial design for development of new TB treatments: A call for innovation.

作者: Christian Lienhardt , Payam Nahid

DOI: 10.1371/JOURNAL.PMED.1002769

关键词: TuberculosisClinical trialAntibiotic resistanceTuberculosis diagnosisPharmacotherapyMEDLINEIntensive care medicineMedicineExtensively drug-resistant tuberculosisClinical study design

摘要: Christian Lienhardt and Payam Nahid launch the Collection on Advances in Clinical Trial Design for Development of New Tuberculosis Treatments.

参考文章(22)
T. E. Tupasi, V. Leimane, E. Nathanson, A. D. Pasechnikov, M. A. Espinal, E. Jaramillo, R. Gupta, P. Huamani, K. Vink, Adverse events in the treatment of multidrug-resistant tuberculosis: results from the DOTS-Plus initiative. International Journal of Tuberculosis and Lung Disease. ,vol. 8, pp. 1382- 1384 ,(2004)
Jacques Grosset, Bacteriologic basis of short-course chemotherapy for tuberculosis. Clinics in Chest Medicine. ,vol. 1, pp. 231- 241 ,(1980) , 10.1016/S0272-5231(21)00072-1
Caminero Ja, Treatment of multidrug-resistant tuberculosis: evidence and controversies. International Journal of Tuberculosis and Lung Disease. ,vol. 10, pp. 829- 837 ,(2006)
G Davies, C Lienhardt, Methodological issues in the design of clinical trials for the treatment of multidrug-resistant tuberculosis: challenges and opportunities. International Journal of Tuberculosis and Lung Disease. ,vol. 14, pp. 528- 537 ,(2010)
Carole D Mitnick, Kenneth G Castro, Mark Harrington, Leonard V Sacks, William Burman, Randomized trials to optimize treatment of multidrug-resistant tuberculosis PLOS Medicine. ,vol. 4, ,(2007) , 10.1371/JOURNAL.PMED.0040292
Maria Tarcela Gler, Vija Skripconoka, Epifanio Sanchez-Garavito, Heping Xiao, Jose L. Cabrera-Rivero, Dante E. Vargas-Vasquez, Mengqiu Gao, Mohamed Awad, Seung-Kyu Park, Tae Sun Shim, Gee Young Suh, Manfred Danilovits, Hideo Ogata, Anu Kurve, Joon Chang, Katsuhiro Suzuki, Thelma Tupasi, Won-Jung Koh, Barbara Seaworth, Lawrence J. Geiter, Charles D. Wells, Delamanid for Multidrug-Resistant Pulmonary Tuberculosis The New England Journal of Medicine. ,vol. 366, pp. 2151- 2160 ,(2012) , 10.1056/NEJMOA1112433
Ann M Ginsberg, Melvin Spigelman, Challenges in tuberculosis drug research and development Nature Medicine. ,vol. 13, pp. 290- 294 ,(2007) , 10.1038/NM0307-290
G. R. Davies, P. P. J. Phillips, T. Jaki, Adaptive clinical trials in tuberculosis : applications, challenges and solutions International Journal of Tuberculosis and Lung Disease. ,vol. 19, pp. 626- 634 ,(2015) , 10.5588/IJTLD.14.0988
Giovanni Battista Migliori, Christian Lienhardt, Karin Weyer, Marieke J. van der Werf, Francesco Blasi, Mario C. Raviglione, Ensuring rational introduction and responsible use of new TB tools: outcome of an ERS multisector consultation European Respiratory Journal. ,vol. 44, pp. 1412- 1417 ,(2014) , 10.1183/09031936.00132114