A case report of ocular tuberculosis in a patient with membranous nephropathy.

作者: Xiaofang Yin , Haibo Ge , Ruifen Miao

DOI: 10.1097/MD.0000000000013892

关键词: TuberculosisMycobacterium tuberculosisBronchoalveolar lavageInternal medicineKidney diseaseMedicineSputumMembranous nephropathyBiopsyHypoproteinemia

摘要: RATIONALE Membranous nephropathy (MN), a chronic kidney disease (CKD), due to hypoproteinemia, malnutrition, anemia, long-term intake of immunosuppressive agents, changes in cellular immune state, and decrease antimicrobial peptides, is high risk for Mycobacterium tuberculosis (MTB) infection, which can cause (TB). TB manifests by various clinical symptoms. Ocular symptoms rare presentation TB. Here, we describe case ocular patient with MN. PATIENT CONCERNS A 63-year-old man membranous (MN) history presented DIAGNOSES According the pathological manifestations tissue biopsy positive polymerase chain reaction (PCR) on samples from sputum bronchoalveolar lavage fluid (BALF), elicited diagnosis disseminated tuberculosis. INTERVENTION The received antituberculous therapy therapy. OUTCOMES significantly improved. LESSONS Clinicians should be aware possibility cases immunocompromised patients perform an appropriate diagnostic work-up

参考文章(6)
Cecilia Lee, Rupesh Agrawal, Carlos Pavesio, Ocular Tuberculosis—A Clinical Conundrum Ocular Immunology and Inflammation. ,vol. 24, pp. 237- 242 ,(2015) , 10.3109/09273948.2014.985387
T.- C. Shen, K.- Y. Huang, C.- H. Chao, Y.- C. Wang, C.- H. Muo, C.- C. Wei, C.- Y. Tu, T.- C. Hsia, C.- M. Shih, W.- H. Hsu, F.- C. Sung, C.- H. Kao, The risk of chronic kidney disease in tuberculosis: a population-based cohort study QJM: An International Journal of Medicine. ,vol. 108, pp. 397- 403 ,(2015) , 10.1093/QJMED/HCU220
Henry M Blumberg, Giovanni B Migliori, Oksana Ponomarenko, Einar Heldal, Tuberculosis on the move The Lancet. ,vol. 375, pp. 2127- 2129 ,(2010) , 10.1016/S0140-6736(10)60574-0
Vasileios S. Skouras, Ioannis Kalomenidis, Pleural fluid tests to diagnose tuberculous pleuritis Current Opinion in Pulmonary Medicine. ,vol. 22, pp. 367- 377 ,(2016) , 10.1097/MCP.0000000000000277
Marcus Ang, Daniel V Vasconcelos-Santos, Kusum Sharma, Massimo Accorinti, Aman Sharma, Amod Gupta, Narsing A Rao, Soon-Phaik Chee, None, Diagnosis of Ocular Tuberculosis Ocular Immunology and Inflammation. ,vol. 26, pp. 208- 216 ,(2018) , 10.1080/09273948.2016.1178304
Alison S Devonshire, Denise M O’Sullivan, Isobella Honeyborne, Gerwyn Jones, Maria Karczmarczyk, Jernej Pavšič, Alice Gutteridge, Mojca Milavec, Pablo Mendoza, Heinz Schimmel, Fran Van Heuverswyn, Rebecca Gorton, Daniela Maria Cirillo, Emanuele Borroni, Kathryn Harris, Marinus Barnard, Anthenette Heydenrych, Norah Ndusilo, Carole L Wallis, Keshree Pillay, Thomas Barry, Kate Reddington, Elvira Richter, Erkan Mozioğlu, Sema Akyürek, Burhanettin Yalçınkaya, Muslum Akgoz, Jana Žel, Carole A Foy, Timothy D McHugh, Jim F Huggett, None, The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis BMC Infectious Diseases. ,vol. 16, pp. 366- 366 ,(2016) , 10.1186/S12879-016-1696-7