The target cell genus does not matter
作者： Sophie Bleves , Thibault G. Sana , Romé Voulhoux
DOI: 10.1016/J.TIM.2014.04.011
关键词: Cell 、 Biology 、 Microbiology 、 Phospholipase 、 Host (biology) 、 Effector 、 Virulence 、 Internalization 、 Enzyme 、 Pseudomonas aeruginosa
摘要: Two type VI secreted phospholipases D of Pseudomonas aeruginosa were identified as trans-kingdom virulence effectors, targeting both prokaryotic and eukaryotic host cells. Each them triggers killing bacterial competitors internalization into non-phagocytic These lipolytic enzymes are widely distributed among pathogens may constitute a conserved strategy.
unirioja.es
sci-hub.se 参考文章(10)
Alistair B. Russell, S. Brook Peterson, Joseph D. Mougous, Type VI secretion system effectors: poisons with a purpose Nature Reviews Microbiology. ,vol. 12, pp. 137- 148 ,(2014) , 10.1038/NRMICRO3185
Feng Jiang, Nicholas R. Waterfield, Jian Yang, Guowei Yang, Qi Jin, A Pseudomonas aeruginosa Type VI Secretion Phospholipase D Effector Targets Both Prokaryotic and Eukaryotic Cells Cell Host & Microbe. ,vol. 15, pp. 600- 610 ,(2014) , 10.1016/J.CHOM.2014.04.010
Thibault G. Sana, Chantal Soscia, Céline M. Tonglet, Steve Garvis, Sophie Bleves, Divergent Control of Two Type VI Secretion Systems by RpoN in Pseudomonas aeruginosa PLoS ONE. ,vol. 8, pp. e76030- ,(2013) , 10.1371/JOURNAL.PONE.0076030
Alistair B. Russell, Michele LeRoux, Krisztina Hathazi, Danielle M. Agnello, Takahiko Ishikawa, Paul A. Wiggins, Sun Nyunt Wai, Joseph D. Mougous, Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors Nature. ,vol. 496, pp. 508- 512 ,(2013) , 10.1038/NATURE12074
Alain Filloux, Sophie Bleves, Thibault G. Sana, Abderrahman Hachani, Iwona Bucior, Chantal Soscia, Steve Garvis, Elise Termine, Joanne Engel, The Second Type VI Secretion System of Pseudomonas aeruginosa Strain PAO1 Is Regulated by Quorum Sensing and Fur and Modulates Internalization in Epithelial Cells Journal of Biological Chemistry. ,vol. 287, pp. 27095- 27105 ,(2012) , 10.1074/JBC.M112.376368
Jennifer L. Edwards, Michael A. Apicella, Neisseria gonorrhoeae PLD directly interacts with Akt kinase upon infection of primary, human, cervical epithelial cells Cellular Microbiology. ,vol. 8, pp. 1253- 1271 ,(2006) , 10.1111/J.1462-5822.2006.00707.X
A. Kierbel, A. Gassama-Diagne, K. Mostov, J. N. Engel, The phosphoinositol-3-kinase-protein kinase B/Akt pathway is critical for Pseudomonas aeruginosa strain PAK internalization Molecular Biology of the Cell. ,vol. 16, pp. 2577- 2585 ,(2005) , 10.1091/MBC.E04-08-0717
John C. Whitney, Christina M. Beck, Young Ah Goo, Alistair B. Russell, Brittany N. Harding, Justin A. De Leon, David A. Cunningham, Bao Q. Tran, David A. Low, David R. Goodlett, Christopher S. Hayes, Joseph D. Mougous, Genetically distinct pathways guide effector export through the type VI secretion system Molecular Microbiology. ,vol. 92, pp. 529- 542 ,(2014) , 10.1111/MMI.12571
Brian T Ho, Tao G Dong, John J Mekalanos, A View to a Kill: The Bacterial Type VI Secretion System Cell Host & Microbe. ,vol. 15, pp. 9- 21 ,(2014) , 10.1016/J.CHOM.2013.11.008
B. Lesic, M. Starkey, J. He, R. Hazan, L. G. Rahme, Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis Microbiology. ,vol. 155, pp. 2845- 2855 ,(2009) , 10.1099/MIC.0.029082-0