Severe oligozoospermia in a patient with myxedema coma

摘要: A case of severe oligozoospermia with myxedema coma is herein presented. The patient was referred to a male infertility clinic 5-year history primary infertility. Decreased serum testosterone and elevated prolactin without abnormal MRI findings in the hypothalamus, decreased semen volume sperm motility were noted. GnRH test revealed luteinizing hormone response, whereas HCG showed normal increase. Because urinalysis after ejaculation indicated retrograde ejaculation, imipramine administration started. However, quality deteriorated, so an ART clinic. Twenty-one months from initial visit, developed loss consciousness edema due coma, life-threatening state hypothyroidism. recovered 1 month thyroid replacement therapy (HRT) corticosteroids. Three analysis (0.2 mL) (two spermatozoa/ejaculate). Elevated levels still present. These parameters gradually improved restoration euthyroidism by HRT. In conclusion, physicians should confirm function management infertility, especially patients levels.