Different requirements for homeotic genes in the soma and germ line of Drosophila

作者: Peter A. Lawrence , Paul Johnston , Gary Struhl

DOI: 10.1016/0092-8674(83)90204-0

关键词: UltrabithoraxengrailedGeneRegulator geneAntennapediaPole cellBiologyGeneticsHomeotic geneHomeotic selector geneGeneral Biochemistry, Genetics and Molecular Biology

摘要: Abstract Some homeotic genes of Drosophila are active only in particular developmental compartments ("selector" genes) whereas others all and responsible for regulating selector gene expression. Using pole cell transplants to generate mosaic females with mutant germ lines, we examine the extent which both classes required during oogenesis. We find that none four ( Ultrabithorax + , Antennapedia Sex combs reduced engrailed ) is development viable eggs, contributes detectable product fertilized zygote. Similarly, neither two regulatory Polycomb extra sex normal However, line contribute functional embryo. These results suggest inactive where they may be regulated by a different mechanism than soma.

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