作者: Peter A. Lawrence , Paul Johnston , Gary Struhl
DOI: 10.1016/0092-8674(83)90204-0
关键词: Ultrabithorax 、 engrailed 、 Gene 、 Regulator gene 、 Antennapedia 、 Pole cell 、 Biology 、 Genetics 、 Homeotic gene 、 Homeotic selector gene 、 General Biochemistry, Genetics and Molecular Biology
摘要: Abstract Some homeotic genes of Drosophila are active only in particular developmental compartments ("selector" genes) whereas others all and responsible for regulating selector gene expression. Using pole cell transplants to generate mosaic females with mutant germ lines, we examine the extent which both classes required during oogenesis. We find that none four ( Ultrabithorax + , Antennapedia Sex combs reduced engrailed ) is development viable eggs, contributes detectable product fertilized zygote. Similarly, neither two regulatory Polycomb extra sex normal However, line contribute functional embryo. These results suggest inactive where they may be regulated by a different mechanism than soma.