Combined effects of high hydrostatic pressure and dispersed oil on the metabolism and the mortality of turbot hepatocytes (Scophthalmus maximus).
作者： Michaël Theron , Alexandra Marziou , Karine Pichavant-Rafini , Stéphane Le Floch , Philippe Lemaire
DOI: 10.1016/J.CHEMOSPHERE.2020.126420
关键词: Metabolism 、 Food science 、 Dispersant 、 Viability assay 、 Scophthalmus 、 Oxygen 、 Context (language use) 、 Turbot 、 Hydrostatic pressure 、 Chemistry
摘要: Abstract Since the DeepWater Horizon oil spill and use at 1450 m depth of dispersant as a technical response, need relevant ecotoxicological data on deep-sea ecosystems becomes crucial. In this context, study focused effect high hydrostatic pressure (10.1 MPa) turbot hepatocytes isolated from fish exposed either to chemically dispersed oil, mechanically or alone. Potential combined effects oil/dispersant pressure, were assessed cell mortality (total death, necrosis apoptosis), viability hepatocyte oxygen consumption (MO2). No change in was observed any experimental conditions, whereas, results showed strong significant increase two groups independently exposure. Finally, exposure have additive cellular level. Presence prevent MO2 our conditions. These mechanistic leading increased energetic demand its eventual inhibition by must be investigated further experiments.
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