Effects of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with prinzmetal's variant angina pectoris

摘要: Abstract To assess the effects of verapamil and nifedipine on left ventricular function at rest during exercise in patients with Prinzmetal's variant angina pectoris, 10 (6 men 4 women a mean age 52 years) were each treated for 2 month periods placebo, (400 ± 80 mg/day, standard deviation [SD]) (82 31 mg/day). During final week treatment period equilibrium gated blood pool scintigraphy was performed exercise. At rest, heart rate therapy lower than nifedipine; systolic pressure volumes ejection fraction similar three interventions. The maximal work load achieved therapy. common to all studies, placebo agents. Thus, wide range neither nor significantly alters or