Head circumference in ELBW babies is associated with learning difficulties and cognition but not ADHD in the school-aged child.

摘要: This study examines whether a small head circumference (HC) and low head-circumference growth velocity (HGV) during the first year of life predict consequences at school age in learning, cognition, concentration. A total 124 extremely-low-birthweight (ELBW) infants (birthweight 500 to 999 g) born between 1977 1986 were eligible for follow-up corrected ages 4, 8, 12 months 2, 6 years. Infants categorized as having HC (< 3% or 3 10%) on basis 1990 British data which allowed standardized z-scores be calculated HC, independent gestation age. HGV measurements using differences z-scores. In 1995, parents 87 children agreed participate learning attention Attention-deficit-hyperactivity disorder (ADHD) was assessed Du Paul Rating Scale. Academic performances based teacher questionnaire dealing with aspects reading, writing, mathematics, spelling. child considered have difficulty if academic problems present least one these four areas. Intellectual ability McCarthy Scale < 10% 8 months' strongly associated school-aged (P=0.004), moderate specificity (70%), positive predictive value (PPV) (67%), sensitivity (67%). = from birth 4 also (P=0.01) higher (98%) PPV (88%) but lower (20%). logistic regression analysis performed risk difficulties dependent variable. Sex, gestation, birthweight, multiple births, history intraventricular hemorrhage did not substantially alter unadjusted odds ratio (4.7; 95% CI 1.9 13.6). Maternal education confound relation. No association found ADHD. (P<0.02), (P=0.02), (P=0.04), (P<0.01) significantly cognitive