Serological, virological and histopathological study of an outbreak of sleeping disease in farmed rainbow trout Oncorhynchus mykiss.
作者： DA Graham , HL Jewhurst , MF McLoughlin , EJ Branson , K McKenzie
DOI: 10.3354/DAO074191
关键词: Rainbow trout 、 Outbreak 、 Viral disease 、 Population 、 Pathology 、 Physiology 、 Serology 、 Oncorhynchus 、 Biology 、 Histopathology 、 Seroprevalence
摘要: ABSTRACT: A prospective longitudinal survey for sleeping disease (SD) was carried out over a 20 wkperiod on caged freshwater population of farmed rainbow trout Oncorhynchus mkyiss . Pancreas,heart and red white skeletal muscle were examined histologically the presence severityof lesions recorded. Sera tested viraemia with Salmonid Alphavirus (SAV) virus neu-tralizing (VN) antibodies. Viraemia detected 4 wk, beginning at Week 6 peakprevalence 57.9% 7. Clinical signs mortalities appeared 8. Total mortality inthe study cage from onward 6.3%, but other cages site had levels upto 47.2%. VN antibodies first 9, seroprevalence increasing to 80% by theend (Week 20). Geometric mean antibody titres peaked 1/89.4 17. Histologi-cal 7 (pancreas only), before in prevalence sever-ity peak Weeks 9 10. The majority resolved 15.KEY WORDS: Sleeping · Rainbow Longitudinal Antibody ·Histopathology
sci-hub.st 参考文章(19)
G. Kärber, BEITRAG ZUR KOLLEKTIVEN BEHANDLUNG PHARMAKOLOGISCHER REIHENVERSUCHE Naunyn-schmiedebergs Archives of Pharmacology. ,vol. 162, pp. 480- 483 ,(1931) , 10.1007/BF01863914
L. Desvignes, C. Quentel, F. Lamour, A. Le Ven, Pathogenesis and immune response in Atlantic salmon (Salmo salar L.) parr experimentally infected with salmon pancreas disease virus (SPDV). Fish & Shellfish Immunology. ,vol. 12, pp. 77- 95 ,(2002) , 10.1006/FSIM.2001.0356
D A Graham, V A Jewhurst, H M Rowley, M F McLoughlin, H Rodger, D Todd, Longitudinal serological surveys of Atlantic salmon, Salmo salar L., using a rapid immunoperoxidase-based neutralization assay for salmonid alphavirus. Journal of Fish Diseases. ,vol. 28, pp. 373- 379 ,(2005) , 10.1111/J.1365-2761.2005.00638.X
G Houghton, Acquired protection in Atlantic salmon Salmo salar parr and post-smolts against pancreas disease Diseases of Aquatic Organisms. ,vol. 18, pp. 109- 118 ,(1994) , 10.3354/DAO018109
Stéphane Villoing, Monique Béarzotti, Stefan Chilmonczyk, Jeannette Castric, Michel Brémont, Rainbow Trout Sleeping Disease Virus Is an Atypical Alphavirus Journal of Virology. ,vol. 74, pp. 173- 183 ,(2000) , 10.1128/JVI.74.1.173-183.2000
M F McLoughlin, R N Nelson, J I McCormick, H M Rowley, D B Bryson, Clinical and histopathological features of naturally occurring pancreas disease in farmed Atlantic salmon, Salmo salar L. Journal of Fish Diseases. ,vol. 25, pp. 33- 43 ,(2002) , 10.1046/J.1365-2761.2002.00334.X
S Kerbart Boscher, M McLoughlin, A Le Ven, J Cabon, M Baud, J Castric, Experimental transmission of sleeping disease in one-year-old rainbow trout, Oncorhynchus mykiss (Walbaum), induced by sleeping disease virus. Journal of Fish Diseases. ,vol. 29, pp. 263- 273 ,(2006) , 10.1111/J.1365-2761.2006.00716.X
MF McLoughlin, RT Nelson, HM Rowley, DI Cox, AN Grant, Experimental pancreas disease in Atlantic salmon Salmo salar post-smolts induced by salmon pancreas disease virus (SPDV) Diseases of Aquatic Organisms. ,vol. 26, pp. 117- 124 ,(1996) , 10.3354/DAO026117
JH Weston, DA Graham, E Branson, HM Rowley, IW Walker, VA Jewhurst, HL Jewhurst, D Todd, Nucleotide sequence variation in salmonid alphaviruses from outbreaks of salmon pancreas disease and sleeping disease. Diseases of Aquatic Organisms. ,vol. 66, pp. 105- 111 ,(2005) , 10.3354/DAO066105
T. M. MURPHY, H. D. RODGER, E. M. DRINAN, F. GANNON, P. KRUSE, W. KORTING, The sequential pathology of pancreas disease in Atlantic salmon farms in Ireland Journal of Fish Diseases. ,vol. 15, pp. 401- 408 ,(1992) , 10.1111/J.1365-2761.1992.TB01239.X