Critical role of hypoxia sensor--HIF-1α in VEGF gene activation. Implications for angiogenesis and tissue injury healing.

作者： A. Ahluwalia , A. S. Tarnawski

关键词: Hypoxia-inducible factors 、 Regulation of gene expression 、 Ischemia 、 Cancer research 、 Angiogenesis 、 Neovascularization 、 HIF1A 、 Downregulation and upregulation 、 Hypoxia (medical) 、 Pathology 、 Biology

摘要: … of blood vessels through the process of angiogenesis – formation of new blood vessels - is … 1), which serves as hypoxia sensor and activates compensatory and adaptive mechanisms. …