Pregnancy loss after frozen-embryo transfer—a comparison of three protocols
作者： Candido Tomás , Birgit Alsbjerg , Hannu Martikainen , Peter Humaidan
DOI: 10.1016/J.FERTNSTERT.2012.07.1058
关键词: Chi-squared distribution 、 Gynecology 、 Andrology 、 Embryo transfer 、 Pregnancy rate 、 Pregnancy test 、 Luteal support 、 Live birth 、 Pregnancy 、 Medicine 、 Positive Pregnancy Test
摘要: Objective To compare the reproductive outcome of three protocols for frozen ET treatment. Design Retrospective follow-up study. Setting Two public clinics and one private clinic. Patient(s) Four thousand four hundred seventy cycles between 2006 and 2010. Intervention(s) Thawing embryos ET. Main Outcome Measure(s) Pregnancy test rate, clinical pregnancy loss rate. Result(s) The natural cycle followed by P (NC + P) was used in 26% cycles, with hCG hCG) 10%, substituted estrogen (E 64% cycles. rate transfers after thawing similar all groups (87.2%, 73.9%, 87.2%, respectively). There a significantly higher positive E (34.3%) NC (35.5%) as compared (26.7%). However, (27.7%, 29.1%, 24.3%, Moreover, no differences were seen regarding live-birth (20.1%, 23.5%, 20.7%, A logistic regression analysis showed that type protocol only predictor loss, while age, irregular endometrial thickness, number, quality transferred did not correlate to loss. Conclusion(s) obtained comparison other protocols; however, due an increased preclinical comparable pregnancy, delivery rates are reported protocols.
fertstert.org
core.ac.uk
sci-hub.se 参考文章(25)
Human Mousavi Fatemi, Dimitra Kyrou, Claire Bourgain, Etienne Van den Abbeel, Georg Griesinger, Paul Devroey, Cryopreserved-thawed human embryo transfer: spontaneous natural cycle is superior to human chorionic gonadotropin-induced natural cycle. Fertility and Sterility. ,vol. 94, pp. 2054- 2058 ,(2010) , 10.1016/J.FERTNSTERT.2009.11.036
Kerstin Bjuresten, Britt-Marie Landgren, Outi Hovatta, Anneli Stavreus-Evers, Luteal phase progesterone increases live birth rate after frozen embryo transfer. Fertility and Sterility. ,vol. 95, pp. 534- 537 ,(2011) , 10.1016/J.FERTNSTERT.2010.05.019
Sérgio Reis Soares, Carlos Troncoso, Ernesto Bosch, Vicente Serra, Carlos Simón, José Remohí, Antonio Pellicer, Age and Uterine Receptiveness: Predicting the Outcome of Oocyte Donation Cycles The Journal of Clinical Endocrinology and Metabolism. ,vol. 90, pp. 4399- 4404 ,(2005) , 10.1210/JC.2004-2252
Ariel Weissman, Eran Horowitz, Amir Ravhon, Zohar Steinfeld, Ravit Mutzafi, Avraham Golan, David Levran, Spontaneous ovulation versus HCG triggering for timing natural-cycle frozen–thawed embryo transfer: a randomized study Reproductive Biomedicine Online. ,vol. 23, pp. 484- 489 ,(2011) , 10.1016/J.RBMO.2011.06.004
Tarek El-Toukhy, Arri Coomarasamy, Mohammed Khairy, Kamal Sunkara, Paul Seed, Yacoub Khalaf, Peter Braude, The relationship between endometrial thickness and outcome of medicated frozen embryo replacement cycles Fertility and Sterility. ,vol. 89, pp. 832- 839 ,(2008) , 10.1016/J.FERTNSTERT.2007.04.031
Vadim Morozov, Jane Ruman, Daniel Kenigsberg, Glenn Moodie, Steven Brenner, Natural cycle cryo-thaw transfer may improve pregnancy outcome Journal of Assisted Reproduction and Genetics. ,vol. 24, pp. 119- 123 ,(2007) , 10.1007/S10815-006-9100-Y
Stine Helgstrand, Anne-Marie Nybo Andersen, Maternal underweight and the risk of spontaneous abortion Acta Obstetricia et Gynecologica Scandinavica. ,vol. 84, pp. 1197- 1201 ,(2005) , 10.1111/J.0001-6349.2005.00706.X
M. Brandes, J.C.M. Verzijden, C.J.C.M. Hamilton, N.P.C. de Weys, J.P. de Bruin, R.S.G.M. Bots, W.L.D.M. Nelen, J.A.M. Kremer, Is the fertility treatment itself a risk factor for early pregnancy loss Reproductive Biomedicine Online. ,vol. 22, pp. 192- 199 ,(2011) , 10.1016/J.RBMO.2010.10.013
HOSSEIN MOZDARANI, SHABNAM Z MORADI, Effect of vitrification on viability and chromosome abnormalities in 8-cell mouse embryos at various storage durations Biological Research. ,vol. 40, pp. 299- 306 ,(2007) , 10.4067/S0716-97602007000400004
Z. Veleva, A. Tiitinen, S. Vilska, C. Hyden-Granskog, C. Tomas, H. Martikainen, J. S. Tapanainen, High and low BMI increase the risk of miscarriage after IVF/ICSI and FET Human Reproduction. ,vol. 23, pp. 878- 884 ,(2008) , 10.1093/HUMREP/DEN017