Solid chirality spectrum testing method of crystal chiral drug
作者： Li Dan , Fang Xueming , Ding Lei , Lin Lirong , Guo Dong
DOI:
关键词: Crystal 、 Analytical chemistry 、 Grinding 、 Chirality (chemistry) 、 Concentration gradient 、 Mixing (process engineering) 、 Spectrum (functional analysis) 、 Materials science
摘要: The invention discloses a solid chirality spectrum testing method of crystal chiral drug. comprises the steps: mixing drug sample with an inertia matrix preset weight ratio, and fully grinding to obtain powder; stepwise diluting according certain concentration gradient within proper range prepare plurality sheet films which are different in value same total weight; respectively performing on each film under condition so as obtained spectrums, analyzing comparing spectrums determine that accurate reliable data obtained. is particularly suitable for characterizing identifying solid-state three-dimensional chemical structure drug, simple visual operate; reliable.
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