Myc represses miR-15a/miR-16-1 expression through recruitment of HDAC3 in mantle cell and other non-Hodgkin B-cell lymphomas
作者： X Zhang , X Chen , J Lin , T Lwin , G Wright
DOI: 10.1038/ONC.2011.470
关键词: Chromatin immunoprecipitation 、 Epigenetics 、 Cancer research 、 Biology 、 Histone 、 Small interfering RNA 、 Histone deacetylase 、 Mantle cell lymphoma 、 Molecular biology 、 Cell cycle 、 microRNA
摘要: … Myc is required for HDAC3 recruitment of DLEU2 promoters. In … of miR-15a/16-1 expression through recruitment of HDAC3. … regulates miRNA expression through recruitment of HDAC …
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Jan-Lukas Robertus, Joost Kluiver, Callista Weggemans, Geert Harms, Rogier M. Reijmers, Yolanthe Swart, Klaas Kok, Stefano Rosati, Ed Schuuring, Gustaaf Van Imhoff, Steven T. Pals, Philip Kluin, Anke Van Den Berg, MiRNA profiling in B non-Hodgkin lymphoma: a MYC-related miRNA profile characterizes Burkitt lymphoma. British Journal of Haematology. ,vol. 149, pp. 896- 899 ,(2010) , 10.1111/J.1365-2141.2010.08111.X
Natalie Meyer, Linda Z. Penn, Reflecting on 25 years with MYC Nature Reviews Cancer. ,vol. 8, pp. 976- 990 ,(2008) , 10.1038/NRC2231
Kathryn A. O'Donnell, Erik A. Wentzel, Karen I. Zeller, Chi V. Dang, Joshua T. Mendell, c-Myc-regulated microRNAs modulate E2F1 expression. Nature. ,vol. 435, pp. 839- 843 ,(2005) , 10.1038/NATURE03677
G M Marshall, S Gherardi, N Xu, Z Neiron, T Trahair, C J Scarlett, D K Chang, P Y Liu, K Jankowski, N Iraci, M Haber, M D Norris, J Keating, E Sekyere, G Jonquieres, F Stossi, B S Katzenellenbogen, A V Biankin, G Perini, T Liu, Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects Oncogene. ,vol. 29, pp. 5957- 5968 ,(2010) , 10.1038/ONC.2010.332
Alexander Pajic, Dimitry Spitkovsky, Barbara Christoph, Bettina Kempkes, Marino Schuhmacher, Martin S. Staege, Markus Brielmeier, Joachim Ellwart, Franz Kohlhuber, Georg W. Bornkamm, Axel Polack, Dirk Eick, Cell cycle activation by c-myc in a Burkitt lymphoma model cell line International Journal of Cancer. ,vol. 87, pp. 787- 793 ,(2000) , 10.1002/1097-0215(20000915)87:6<787::AID-IJC4>3.0.CO;2-6
Jan Davidson-Moncada, F. Nina Papavasiliou, Wayne Tam, MicroRNAs of the immune system: roles in inflammation and cancer. Annals of the New York Academy of Sciences. ,vol. 1183, pp. 183- 194 ,(2010) , 10.1111/J.1749-6632.2009.05121.X
R I Aqeilan, G A Calin, C M Croce, miR-15a and miR-16-1 in cancer: discovery, function and future perspectives Cell Death & Differentiation. ,vol. 17, pp. 215- 220 ,(2010) , 10.1038/CDD.2009.69
Elena Hartmann, Verònica Fernàndez, Victor Moreno, Joan Valls, Luis Hernández, Francesc Bosch, Pau Abrisqueta, Wolfram Klapper, Martin Dreyling, Eva Hoster, Hans Konrad Müller-Hermelink, German Ott, Andreas Rosenwald, Elías Campo, Five-Gene Model to Predict Survival in Mantle-Cell Lymphoma Using Frozen or Formalin-Fixed, Paraffin-Embedded Tissue Journal of Clinical Oncology. ,vol. 26, pp. 4966- 4972 ,(2008) , 10.1200/JCO.2007.12.0410
Carlo M. Croce, Causes and consequences of microRNA dysregulation in cancer Nature Reviews Genetics. ,vol. 10, pp. 704- 714 ,(2009) , 10.1038/NRG2634
Bálint Nagy, Tuija Lundán, Marcelo L. Larramendy, Yan Aalto, Ying Zhu, Tarja Niini, Henrik Edgren, Anna Ferrer, Juhani Vilpo, Erkki Elonen, Kim Vettenranta, Kaarle Franssila, Sakari Knuutila, Abnormal expression of apoptosis-related genes in haematological malignancies: overexpression of MYC is poor prognostic sign in mantle cell lymphoma. British Journal of Haematology. ,vol. 120, pp. 434- 441 ,(2003) , 10.1046/J.1365-2141.2003.04121.X