Early Virus Clearance and Delayed Antibody Response in a Case of Coronavirus Disease 2019 (COVID-19) With a History of Coinfection With Human Immunodeficiency Virus Type 1 and Hepatitis C Virus.
作者： Juanjuan Zhao , Xuejiao Liao , Haiyan Wang , Lanlan Wei , Mingzhao Xing
DOI: 10.1093/CID/CIAA408
关键词: Coronavirus disease 2019 (COVID-19) 、 Virus 、 Antibody response 、 Virology 、 Coinfection 、 Antibody 、 Hepatitis C virus 、 Human immunodeficiency virus (HIV) 、 RNA 、 Medicine
摘要: The effect of host immune status on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains unknown. Here, we report the first case disease 2019 (COVID-19) with human immunodeficiency virus type 1 (HIV-1)/hepatitis C coinfection, who showed a persistently negative SARS-CoV-2 RNA test but delayed antibody response in plasma. This highlights influence HIV-1-induced dysfunction early clearance.
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