Prognostic significance of DNA replication errors in young patients with colorectal cancer.

作者: Jeffrey R. Lukish , Kenji Muro , John DeNobile , Rachel Katz , John Williams

DOI: 10.1097/00000658-199801000-00008

关键词: Internal medicineNeoplasm stagingImmunologyPolymerase chain reactionRetrospective cohort studyMedicineDNA replicationRectumOncologyPredictive value of testsColorectal cancerSurvival analysis

摘要: … RER status of a well-defined group of young patients with CRC and to compare the clinical and pathologic characteristics of RER-positive and RER-… to evaluate tumor cells with the RER …

参考文章(23)
B. Vogelstein, J. K. V. Willson, R. Parsons, S. D. Markowitz, E. Z. Lang, G. K. Bowerfind, W. D. Sedwick, M. L. Veigl, J. R. Eshleman, Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer. Oncogene. ,vol. 10, pp. 33- 37 ,(1995)
Henry T. Lynch, Thomas C. Smyrk, Patrice Watson, Stephen J. Lanspa, Jane F. Lynch, Patrick M. Lynch, R.Jennifer Cavalieri, C.Richard Boland, Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review Gastroenterology. ,vol. 104, pp. 1535- 1549 ,(1993) , 10.1016/0016-5085(93)90368-M
Hoguen Kim, Jin Jen, Bert Vogelstein, Stanley R Hamilton, None, Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences American Journal of Pathology. ,vol. 145, pp. 148- 156 ,(1994)
A. J. Mcilwrath, A. R. M. Edlin, W. M. Gallagher, R. Brown, D. A. Anthoney, Microsatellite Instability, Apoptosis, and Loss of p53 Function in Drug-resistant Tumor Cells Cancer Research. ,vol. 56, pp. 1374- 1381 ,(1996)
Lauri A. Aaltonen, Bert Vogelstein, Jukka Pekka Mecklin, Kenneth W. Kinzler, Jeremy R. Jass, Patrice Watson, Henry T. Lynch, Stanley R. Hamilton, Päivi Peltomäki, Pertti Sistonen, Matti Juhola, Albert de la Chapelle, Jane S. Green, Gustav Tallqvist, Heikki Järvinen, Replication Errors in Benign and Malignant Tumors from Hereditary Nonpolyposis Colorectal Cancer Patients Cancer Research. ,vol. 54, pp. 1645- 1648 ,(1994)
G. Aquilina, P. Hess, P. Branch, C. MacGeoch, I. Casciano, P. Karran, M. Bignami, A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 8905- 8909 ,(1994) , 10.1073/PNAS.91.19.8905
M. S. Rhyu, Molecular Mechanisms Underlying Hereditary Nonpolyposis Colorectal Carcinoma Journal of the National Cancer Institute. ,vol. 88, pp. 240- 251 ,(1996) , 10.1093/JNCI/88.5.240
S. L. Parker, T. Tong, S. Bolden, P. A. Wingo, Cancer statistics, 1997 CA: A Cancer Journal for Clinicians. ,vol. 47, pp. 5- 27 ,(1997) , 10.3322/CANJCLIN.47.1.5
P. Branch, G. Aquilina, M. Bignami, P. Karran, Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage Nature. ,vol. 362, pp. 652- 654 ,(1993) , 10.1038/362652A0
N. P. Bhattacharyya, A. Skandalis, A. Ganesh, J. Groden, M. Meuth, Mutator phenotypes in human colorectal carcinoma cell lines Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 6319- 6323 ,(1994) , 10.1073/PNAS.91.14.6319