Role of Phytomolecules in the Treatment of Obesity: Targets, Mechanisms and Limitations.

摘要: Obesity has become a worldwide health problem. It triggers additional co-morbidities like cardiovascular diseases, cancer, depression, sleep disorders, gastrointestinal problems and many more. Excess accumulation of fat in obesity could be caused by factors sedentary lifestyle, consumption high diet, genetic predisposition, etc. Imbalanced energy metabolism i.e., greater than utilisation, invariably underlies obesity. Considering the prevalence continuous, uncontrolled increase this major public issue, there is an urgent need to find appropriate therapeutic agents with minimal or no side effects. The recent years led surge number drugs available market that claim control Although long list medicines management strategies are available, selecting right intervention feasible challenge. Several phytochemicals hydroxycitric acid, flavonoids, tannins, anthocyanins, phytohaemagglutins, thymoquinone epigallocatechin gallate have been shown possess promising anti-obesity properties. However, studies providing information on how various exert their effects inadequate. This calls for more experimentation less explored area research. Additionally, complication arises when it result multiple associated co-morbidities. In order handle such complexities combinatorial interventions effective. review, we described medicinal chemistry different highly effective which can used treatment