Advanced magnetic resonance imaging methods for planning and monitoring radiation therapy in patients with high-grade glioma.

摘要: This review explores how the integration of advanced imaging methods with high-quality anatomical images significantly improves characterization, target definition, assessment response to therapy, and overall management patients high-grade glioma. Metrics derived from diffusion-, perfusion-, susceptibility-weighted magnetic resonance in conjunction spectroscopic imaging, allows us characterize regions edema, hypoxia, increased cellularity, necrosis within heterogeneous tumor surrounding brain tissue. Quantification such measures may provide a more reliable initial representation delineation therapy than changes contrast-enhancing or T2 lesion alone have significant effect on targeting resection, planning radiation, assessing treatment effectiveness. In long term, implementation these methodologies can also aid identification recurrent its differentiation treatment-related confounds facilitate detection radiationinduced vascular injury otherwise normal-appearing