Mannich bases in medicinal chemistry and drug design.

作者: Gheorghe Roman

DOI: 10.1016/J.EJMECH.2014.10.076

关键词: Platelet aggregationCombinatorial chemistryDrugMannich reactionAntifungalAntiparasiticAntimycobacterial AgentsMedicinal chemistryBiological activityChemistry

摘要: … Under normal reaction conditions, substitution of a substrate with a single aminomethyl function results in mono-Mannich bases, but two aminomethyl groups may also be grafted onto a …

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