Thalamic-Caudal Zona Incerta Deep Brain Stimulation for Refractory Orthostatic Tremor: A Report of 3 Cases.
作者： Dilan Athauda , Dejan Georgiev , Iciar Aviles-Olmos , Amy Peters , Brian Day
DOI: 10.1002/MDC3.12345
关键词: Zona incerta 、 Thalamus 、 Ventral intermediate nucleus 、 Orthostatic tremor 、 Caudal Zona Incerta 、 Refractory 、 Deep brain stimulation 、 Anesthesia 、 Spinal cord 、 Medicine
摘要: Orthostatic tremor (OT) is a rare, disabling movement disorder characterized by the development of high-frequency lower limbs and feelings unsteadiness upon standing, which compel patient to sit down or walk. Medical therapy often unsatisfactory. Previous reports suggest that deep brain stimulation ventral intermediate nucleus thalamus may improve clinical outcomes. The authors report 3 patients who had intractable orthostatic treated with bilateral thalamus-caudal zona incerta, resulting in improved sustained improvements symptoms, although there were no apparent changes underlying frequency onset.
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