Preparation of omeprazole and lansoprazole

作者： Bob Macel , Clarke Slemon

DOI:

关键词: Organic chemistry 、 Lansoprazole 、 Omeprazole 、 Amide 、 Carboxylate 、 Chemistry 、 Salt (chemistry) 、 Alkaline hydrolysis (body disposal) 、 Decarboxylation

摘要: Omeprazole and lansoprazole, which are chemically pyridine-benzimidazole sulfinyl compounds, produced from the corresponding acetamide-sulfide compounds by a process of oxidation to form amide compound, followed alkaline hydrolysis carboxylate or salt, decarboxylation.