An update on the use of massive transfusion protocols in obstetrics

作者: Steven L. Clark , Gary D.V. Hankins , Luis D. Pacheco , George R. Saade , Maged M. Costantine

DOI: 10.1016/J.AJOG.2015.08.068

关键词: Hemostatic resuscitationMedicinePROTHROMBIN COMPLEXMassive transfusionIntensive care medicineResuscitationAlternative treatmentBlood transfusionTranexamic acidEarly activation

摘要: Obstetrical hemorrhage remains a leading cause of maternal mortality worldwide. New concepts involving the pathophysiology of hemorrhage have been described and include early activation of both the protein C and fibrinolytic pathways. New strategies in hemorrhage treatment include the use of hemostatic resuscitation, although the optimal ratio to administer the various blood products is still unknown. Massive transfusion protocols involve the early utilization of blood products and limit the traditional approach of early …

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