Labeling of human epidermal stem cells
作者： Norbert Fusenig , Sonja Muffler , Hans-Jürgen Stark , Petra Boukamp , Mara Amoros-Alonso
DOI:
关键词: Stem cell 、 Biology 、 Pathology 、 Cell biology 、 Medical treatment
摘要: The present invention provides skin equivalents comprising human epidermal stem cells which are specifically labeled. labeling is carried out with a marker capable of slowly proliferating cells, e.g. iododeoxyuridine or PKH26. Particularly, the labeled cells. also corresponding uses and methods using such cultures, in fields research medical treatment diseases.
lens.org 参考文章(12)
Eric Sun-Yin Chan, Ping Kuen Lam, Material and method for engraftment of a composite biocompatible skin graft on the neodermis of artificial skin ,(1999)
Robert M. Lavker, Tung-Tien Sun, George Cotsarelis, Method of identifying and modulating the activity of label retaining cells in hair follicles for diagnostic and therapeutic purposes ,(1992)
Zheng-Pin Wang, Methods of preparing a transplantable product for treatment of skin defects ,(2003)
Martine Dunnwald, Jackie R. Bickenbach, Methods to prepare and use epidermal stem cells ,(2001)
Seung Kim, Yuichi Hori, Insulin-producing cells derived from stem cells ,(2004)
Rainer Kollmar, Nikolaus Gassler, Martin Maurer, Clemens Sommer, Stefan Schwab, Wolf-Ruediger Schaebitz, Carola Krueger, Armin Schneider, Daniela Weber, Methods of treating neurological conditions with hematopoeitic growth factors ,(2007)
R. Lavker, T. Sun, Heterogeneity in epidermal basal keratinocytes: morphological and functional correlations Science. ,vol. 215, pp. 1239- 1241 ,(1982) , 10.1126/SCIENCE.7058342
M. Dunnwald, A. Tomanek-Chalkley, D. Alexandrunas, J. Fishbaugh, J. R. Bickenbach, Isolating a pure population of epidermal stem cells for use in tissue engineering. Experimental Dermatology. ,vol. 10, pp. 45- 54 ,(2001) , 10.1034/J.1600-0625.2001.100106.X
Alvaro Meana, Sara G. Llames, Marcela Del Rio, Fernando Larcher, Eva García, Marta García, María José Escamez, Jose L. Jorcano, Purificación Holguín, Human plasma as a dermal scaffold for the generation of a completely autologous bioengineered skin. Transplantation. ,vol. 77, pp. 350- 355 ,(2004) , 10.1097/01.TP.0000112381.80964.85
Hans-Jürgen Stark, Michael J. Willhauck, Nicolae Mirancea, Karsten Boehnke, Iris Nord, Dirk Breitkreutz, Alessandra Pavesio, Petra Boukamp, Norbert E. Fusenig, Authentic fibroblast matrix in dermal equivalents normalises epidermal histogenesis and dermo-epidermal junction in organotypic co-culture European Journal of Cell Biology. ,vol. 83, pp. 631- 645 ,(2004) , 10.1078/0171-9335-00435