Optimal Reversal of Novel Anticoagulants in Trauma

摘要: The incidence of patients with trauma on novel oral anticoagulants (NOACs) for the treatment thromboembolic disorders is increasing. In severe bleeding or hemorrhage into critical spaces, urgent reversal this underlying pharmacologic coagulopathy becomes paramount. Optimal strategy commonly used NOACs still evolving. Basic tenets evaluation and resuscitation remain same. Clinical outcomes data in human are lacking, but needed to establish efficacy safety these treatments. This article summarizes available evidence provides optimal NOACs.