Tandem organocatalytic approach to C28–C35 fragment of eribulin mesylate
作者： Lahu N. Chavan , Rambabu Chegondi , Srivari Chandrasekhar
DOI: 10.1016/J.TETLET.2015.05.075
关键词: Total synthesis 、 Stereochemistry 、 Fragment (logic) 、 Tandem 、 Eribulin Mesylate 、 Anticancer drug 、 Chemistry
摘要: The organocatalytic approach is devised for the synthesis of C28–C35 fragment anticancer drug eribulin mesylate (Halaven®) amenable scaleup toward total synthesis.
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