Mitochondrial DNA in innate immune responses and inflammatory pathology
作者： A. Phillip West , Gerald S. Shadel
DOI: 10.1038/NRI.2017.21
关键词: Immunity 、 Mitochondrial DNA 、 Extracellular 、 Pattern recognition receptor 、 Innate immune system 、 Biology 、 Mitochondrion 、 Pathology 、 Immunology 、 Receptor 、 Interferon
摘要: … activation, increase type I IFN responses and enhance … mtDNA in type I IFN responses. In addition to an intracellular role for mtDNA in triggering type I IFN responses, mtDNA released …
nature.com
sci-hub.se 参考文章(120)
Elliott D. Crouser, Guohong Shao, Mark W. Julian, Jennifer E. Macre, Gerald S. Shadel, Susheela Tridandapani, Qin Huang, Mark D. Wewers, Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors. Critical Care Medicine. ,vol. 37, pp. 2000- 2009 ,(2009) , 10.1097/CCM.0B013E3181A001AE
M. Patrushev, V. Kasymov, V. Patrusheva, T. Ushakova, V. Gogvadze, A. Gaziev, Mitochondrial permeability transition triggers the release of mtDNA fragments. Cellular and Molecular Life Sciences. ,vol. 61, pp. 3100- 3103 ,(2004) , 10.1007/S00018-004-4424-1
Samuel E. Weinberg, Laura A. Sena, Navdeep S. Chandel, Mitochondria in the regulation of innate and adaptive immunity. Immunity. ,vol. 42, pp. 406- 417 ,(2015) , 10.1016/J.IMMUNI.2015.02.002
Sébastien Calvignac, Lara Konecny, Florian Malard, Christophe J. Douady, Preventing the pollution of mitochondrial datasets with nuclear mitochondrial paralogs (numts) Mitochondrion. ,vol. 11, pp. 246- 254 ,(2011) , 10.1016/J.MITO.2010.10.004
Anthony Rongvaux, Ruaidhrí Jackson, Christian C.D. Harman, Tuo Li, A. Phillip West, Marcel R. de Zoete, Youtong Wu, Brian Yordy, Saquib A. Lakhani, Chia-Yi Kuan, Tadatsugu Taniguchi, Gerald S. Shadel, Zhijian J. Chen, Akiko Iwasaki, Richard A. Flavell, Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA Cell. ,vol. 159, pp. 1563- 1577 ,(2014) , 10.1016/J.CELL.2014.11.037
Leonardo Lorente, Ruth Iceta, María M. Martín, Esther López-Gallardo, Jordi Solé-Violán, José Blanquer, Lorenzo Labarta, César Díaz, Juan María Borreguero-León, Alejandro Jiménez, Julio Montoya, Eduardo Ruiz-Pesini, Severe Septic Patients with Mitochondrial DNA Haplogroup JT Show Higher Survival Rates: A Prospective, Multicenter, Observational Study PLoS ONE. ,vol. 8, pp. e73320- ,(2013) , 10.1371/JOURNAL.PONE.0073320
Noemí García, Edmundo Chávez, Mitochondrial DNA fragments released through the permeability transition pore correspond to specific gene size. Life Sciences. ,vol. 81, pp. 1160- 1166 ,(2007) , 10.1016/J.LFS.2007.08.019
Kenichi Shimada, Timothy R. Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V. Krishnan Ramanujan, Andrea J. Wolf, Laurent Vergnes, David M. Ojcius, Altan Rentsendorj, Mario Vargas, Candace Guerrero, Yinsheng Wang, Katherine A. Fitzgerald, David M. Underhill, Terrence Town, Moshe Arditi, Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis Immunity. ,vol. 36, pp. 401- 414 ,(2012) , 10.1016/J.IMMUNI.2012.01.009
Michael J. White, Kate McArthur, Donald Metcalf, Rachael M. Lane, John C. Cambier, Marco J. Herold, Mark F. van Delft, Sammy Bedoui, Guillaume Lessene, Matthew E. Ritchie, David C.S. Huang, Benjamin T. Kile, Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production Cell. ,vol. 159, pp. 1549- 1562 ,(2014) , 10.1016/J.CELL.2014.11.036
Qin Zhang, Kiyoshi Itagaki, Carl J. Hauser, Mitochondrial DNA is released by shock and activates neutrophils via p38 map kinase. Shock. ,vol. 34, pp. 55- 59 ,(2010) , 10.1097/SHK.0B013E3181CD8C08