Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers

作者: Mcquiston Beth , Marino Jaime , Rogers Justin , Zhang Tianming , Datwyler Saul

DOI:

关键词: Biomarker (medicine)MedicineMagnetic resonance imagingPathologyGlial fibrillary acidic protein

摘要: Disclosed herein are methods that aid in the determination of whether to perform imaging, such as magnetic resonance imaging (MRI) or computerized tomography (CT) scan, on a human subject has sustained may have an injury head using early biomarker, ubiquitin carboxy-terminal hydrolase LI (UCH-L1), glial fibrillary acidic protein (GFAP), combination thereof. These involve detecting levels and changes UCH-L1 and/or GFAP samples taken from at time points within 24 hours after head.

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