Methods for inhibiting angiogenesis

作者: Keith R. Laderoute , Nahid Waleh , Daniel Tuse , Charles Hiebert

DOI:

关键词: Cancer researchMedicineTumor necrosis factor alphaAngiogenesis

摘要: The present invention relates to methods for effectively inhibiting unwanted angiogenesis. More particularly, this of treating diseases that show angiogenesis and delivering anti-angiogenic activity a mammal. In other aspects reducing the level tumor necrosis factor α.

参考文章(21)
Nahid S. Waleh, Brian J. Murphy, Robert M. Sutherland, Tandora D. Grant, Randall H. Kramer, John Gallo, Selective Down-Regulation of Integrin Receptors in Spheroids of Squamous Cell Carcinoma Cancer Research. ,vol. 54, pp. 838- 843 ,(1994)
Kim Lee Sim, Judah M. Folkman, Yihai Cao, Michael S. O'reilly, Angiostatin and method of use for inhibition of angiogenesis ,(1995)
Xiaoying Chen, Polly Pine, A.Merrill Knapp, Daniel Tusé, Keith R. Laderoute, Oncocidin A1: a novel tubulin-binding drug with antitumor activity against human breast and ovarian carcinoma xenografts in nude mice. Biochemical Pharmacology. ,vol. 56, pp. 623- 633 ,(1998) , 10.1016/S0006-2952(98)00210-X
Rakesh K. Jain, Karleheinz Schlenger, Michael Hockel, Fan Yuan, Quantitative angiogenesis assays: Progress and problems Nature Medicine. ,vol. 3, pp. 1203- 1208 ,(1997) , 10.1038/NM1197-1203
Kevin J. Tracey, Yuman Fong, David G. Hesse, Kirk R. Manogue, Annette T. Lee, George C. Kuo, Stephen F. Lowry, Anthony Cerami, Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia Nature. ,vol. 330, pp. 662- 664 ,(1987) , 10.1038/330662A0
Robert Auerbach, Louis Kubai, David Knighton, Judah Folkman, A simple procedure for the long-term cultivation of chicken embryos☆ Developmental Biology. ,vol. 41, pp. 391- 394 ,(1974) , 10.1016/0012-1606(74)90316-9
J Folkman, R Langer, R. Linhardt, C Haudenschild, S Taylor, Angiogenesis inhibition and tumor regression caused by heparin or a heparin fragment in the presence of cortisone Science. ,vol. 221, pp. 719- 725 ,(1983) , 10.1126/SCIENCE.6192498
Spencer L. Tripp, Fred B. Block, George Barile, Synthesis of methylene- and carbonyl-bridged analogs of iodothyronines and iodothyroacetic acids. Journal of Medicinal Chemistry. ,vol. 16, pp. 60- 64 ,(1973) , 10.1021/JM00259A017
Stephanie Taylor, Judah Folkman, Protamine is an inhibitor of angiogenesis Nature. ,vol. 297, pp. 307- 312 ,(1982) , 10.1038/297307A0
R. O. Williams, M. Feldmann, R. N. Maini, Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 9784- 9788 ,(1992) , 10.1073/PNAS.89.20.9784