MicroRNAs as regulators of cell death mechanisms in amyotrophic lateral sclerosis

作者: Delia Gagliardi , Giacomo P. Comi , Nereo Bresolin , Stefania Corti

DOI: 10.1111/JCMM.13976

关键词: NeuroscienceAmyotrophic lateral sclerosisRegulation of gene expressionProgrammed cell deathProgressive neurodegenerative disorderNecroptosisParalysisApoptosisBiologymicroRNA

摘要: … miR-206 level is increased in skeletal muscles in both SOD1 and … in the miR-206 level in skeletal muscle28, 29 and in serum … For this reason, it was proposed that FUS/miR-375/ELAVL4 …

参考文章(83)
Yanchun Chen, Hongmei Du, Yingjun Guan, Fenghua Zhou, Xin Wang, Bing Liu, Caixia Zhang, Li Yu, Hailing Gao, miRNA-9 expression is upregulated in the spinal cord of G93A-SOD1 transgenic mice. International Journal of Clinical and Experimental Pathology. ,vol. 6, pp. 1826- 1838 ,(2013)
Valeria Valsecchi, Marina Boido, Elena De Amicis, Antonio Piras, Alessandro Vercelli, Expression of Muscle-Specific MiRNA 206 in the Progression of Disease in a Murine SMA Model PLOS ONE. ,vol. 10, pp. 0- 0 ,(2015) , 10.1371/JOURNAL.PONE.0128560
Rohini Raman, Scott P Allen, Emily F Goodall, Shelley Kramer, Lize-Linde Ponger, Paul R. Heath, Marta Milo, Hannah C. Hollinger, Theresa Walsh, J Robin Highley, Simon Olpin, Christopher J. McDermott, Pamela J. Shaw, Janine Kirby, Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia‐response and RNA processing functions Neuropathology and Applied Neurobiology. ,vol. 41, pp. 201- 226 ,(2015) , 10.1111/NAN.12147
Oleg Butovsky, Mark P. Jedrychowski, Ron Cialic, Susanne Krasemann, Gopal Murugaiyan, Zain Fanek, David J. Greco, Pauline M. Wu, Camille E. Doykan, Olga Kiner, Robert J. Lawson, Matthew P. Frosch, Nathalie Pochet, Rachid El Fatimy, Anna M. Krichevsky, Steven P. Gygi, Hans Lassmann, James Berry, Merit E. Cudkowicz, Howard L. Weiner, Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice Annals of Neurology. ,vol. 77, pp. 75- 99 ,(2015) , 10.1002/ANA.24304
Srikanth Ranganathan, Robert Bowser, p53 and Cell Cycle Proteins Participate in Spinal Motor Neuron Cell Death in ALS The Open Pathology Journal. ,vol. 4, pp. 11- 22 ,(2010) , 10.2174/1874375701004010011
J. Sreedharan, I. P. Blair, V. B. Tripathi, X. Hu, C. Vance, B. Rogelj, S. Ackerley, J. C. Durnall, K. L. Williams, E. Buratti, F. Baralle, J. de Belleroche, J. D. Mitchell, P. N. Leigh, A. Al-Chalabi, C. C. Miller, G. Nicholson, C. E. Shaw, TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis Science. ,vol. 319, pp. 1668- 1672 ,(2008) , 10.1126/SCIENCE.1154584
Akshay Bhinge, Seema C. Namboori, Angela Bithell, Chiara Soldati, Noel J. Buckley, Lawrence W. Stanton, MiR‐375 is Essential for Human Spinal Motor Neuron Development and May Be Involved in Motor Neuron Degeneration Stem Cells. ,vol. 34, pp. 124- 134 ,(2016) , 10.1002/STEM.2233
Anna Emde, Chen Eitan, Lee‐Loung Liou, Ryan T Libby, Natali Rivkin, Iddo Magen, Irit Reichenstein, Hagar Oppenheim, Raya Eilam, Aurelio Silvestroni, Betty Alajajian, Iddo Z Ben‐Dov, Julianne Aebischer, Alon Savidor, Yishai Levin, Robert Sons, Scott M Hammond, John M Ravits, Thomas Möller, Eran Hornstein, Dysregulated miRNA biogenesis downstream of cellular stress and ALS‐causing mutations: a new mechanism for ALS The EMBO Journal. ,vol. 34, pp. 2633- 2651 ,(2015) , 10.15252/EMBJ.201490493
Axel Freischmidt, Kathrin Müller, Lisa Zondler, Patrick Weydt, Benjamin Mayer, Christine A.F. von Arnim, Annemarie Hübers, Johannes Dorst, Markus Otto, Karlheinz Holzmann, Albert C. Ludolph, Karin M. Danzer, Jochen H. Weishaupt, Serum microRNAs in sporadic amyotrophic lateral sclerosis. Neurobiology of Aging. ,vol. 36, pp. 2660- ,(2015) , 10.1016/J.NEUROBIOLAGING.2015.06.003
Xiaoying Wang, Peng Liu, Hua Zhu, Yanfeng Xu, Chunmei Ma, Xiaowei Dai, Lan Huang, Yali Liu, Lianfeng Zhang, Chuan Qin, miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation. Brain Research Bulletin. ,vol. 80, pp. 268- 273 ,(2009) , 10.1016/J.BRAINRESBULL.2009.08.006