Protective action of nipradilol mediated through S-nitrosylation of Keap1 and HO-1 induction in retinal ganglion cells

作者: Yoshiki Koriyama , Marie Kamiya , Tsuneo Takadera , Kunizo Arai , Kayo Sugitani

DOI: 10.1016/J.NEUINT.2012.09.004

关键词: KEAP1Retinal ganglion cellS-NitrosylationRetinal ganglionNipradilolNeuroprotectionCell biologyOxidative stressNIPAnatomyChemistry

摘要: … binding of Nrf2 to the HO-1 enhancer E1 element of genomic HO-1 DNA. ChIP assays with an … HO-1 immunohistochemistry in the mouse retina. Panels (A–C) show the untreated retina. …

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