作者: Martin Kragl , Eckhard Lammert
DOI: 10.1007/978-90-481-3271-3_10
关键词: Islet 、 Pancreatic islet function 、 Insulin 、 Biology 、 Basement membrane 、 Immunology 、 Laminin 、 Secretion 、 Cancer research 、 Transplantation 、 Blood vessel
摘要: Clinical treatment of diabetic patients by islet transplantation faces various complications. At present, in vitro expansion islets occurs at the cost their essential features, which are insulin production and release. However, recent discovery blood vessel/β-cell interactions as an important aspect transcription, secretion, proliferation might point us to ways how this problem could be overcome.