Basement Membrane in Pancreatic Islet Function

作者: Martin Kragl , Eckhard Lammert

DOI: 10.1007/978-90-481-3271-3_10

关键词: IsletPancreatic islet functionInsulinBiologyBasement membraneImmunologyLamininSecretionCancer researchTransplantationBlood vessel

摘要: Clinical treatment of diabetic patients by islet transplantation faces various complications. At present, in vitro expansion islets occurs at the cost their essential features, which are insulin production and release. However, recent discovery blood vessel/β-cell interactions as an important aspect transcription, secretion, proliferation might point us to ways how this problem could be overcome.

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