Association Between Prophylactic Antibiotic Use and Surgical Site Infection Based on Quality Assessment Data in Korea

摘要: OBJECTIVES To examine the prophylactic antibiotic use in reducing surgical site infection. METHODS This was a retrospective study for patients aged 18 years and older who underwent gastrectomy, cholecystectomy, colectomy, cesarean section hysterectomy. The data source quality assessment of Health Insurance Review & Assessment Service gathered from medical records 302 national hospitals. Prophylactic defined as: timely administration or inappropriate selection. We performed hierarchical logistic regression to association between infection with adjustment covariates. RESULTS population consisted 16, 348 (1,588 gastrectomies, 2,327 cholecystectomies, 1,384 colectomies, 3,977 hysterectomies 7,072 sections) identified 351 (2.1%) patients. rates selection varied according procedures. Cholecystectomy received had significantly reduced risk compared those did not receive antibiotics (OR 0.64, 95% CI=0.50-0.83), but no significant reduction observed other When were given, increased: 8.26-fold (95% CI=4.34-15.7) 4.73-fold CI=2.09-10.7) 2.34-fold CI=1.14-4.80) section, 4.03-fold CI=1.93-8.42) CONCLUSIONS examines among administration, Patients appropriate decreased Efforts improve timing are needed lower