NaGdF4:Yb3+/Er3+@NaGdF4:Nd3+@Sodium-Gluconate: Multifunctional and Biocompatible Ultrasmall Core–Shell Nanohybrids for UCL/MR/CT Multimodal Imaging
作者： Dandan Ma , Lingjie Meng , Yuzhong Chen , Min Hu , Yanke Chen
关键词: Nanoparticle 、 Biocompatibility 、 Dispersity 、 Nuclear chemistry 、 Fourier transform infrared spectroscopy 、 Materials science 、 Sodium gluconate 、 Transmission electron microscopy 、 Ligand 、 Nanotechnology 、 Laser
摘要: Multimodal bioimaging nanoparticles by integrating diverse imaging ingredients into one system, represent a class of emerging advanced materials that provide more comprehensive and accurate clinical diagnostics than conventional contrast agents. Here monodisperse biocompatible core–shell nanoparticles, NaGdF4: Yb3+/Er3+@NaGdF4:Nd@sodium-gluconate (termed as GNa-Er@Nd), with about 26 nm in diameter were successfully prepared facile two step reactions high boiling solvents, followed ligand exchange process sodium gluconate. The resulting GNa-Er@Nd well characterized transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectra (FTIR), zeta potentials. These nanohybrids present brightly dual-wavelength excited upconversion luminescence (UCL) under both 980 793 laser because the synergistic effect Yb3+/Er3+ Nd3+. They also exhibited excellent relaxivity parameters (r1) magnetic resonance (MRI) an...
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