作者: Wouter W. de Herder , Diego Ferone , Dik J. Kwekkeboom , Steven W. J. Lamberts
DOI: 10.1007/978-1-4615-4341-1_3
关键词: Prolactin 、 Endocrinology 、 Adrenocorticotropic hormone 、 Hormone 、 Thyroid-stimulating hormone 、 Pituitary tumors 、 Hypopituitarism 、 Medicine 、 Malignancy 、 Internal medicine 、 Pituitary adenoma
摘要: Several neoplastic and non-neoplastic lesions may arise within the sellar parasellar regions (Table 1). Among these, pituitary adenomas are most common. Almost all tumors benign, although they display signs of local invasion or show histological evidence malignancy. However, generally these can be designated malignant only when distant metastases present. Adenomas with a diameter less than 10 mm classified as microadenomas, whereas those greater considered macroadenomas. Pituitary subclassified into clinically functioning — according to hormone secreted non-functioning. products prolactin (PRL), growth (GH), adrenocorticotropic (ACTH), thyroid stimulating (TSH), gonadotropins (LH FSH), glycoprotein subunits (SU) mixtures products. The majority so-called macroadenomas either secrete inappropriate amounts hormones, inactive hormonal fragments. differential diagnosis is currently based on clinical, endocrinological radiological characteristics. Active hormone-secreting easily diagnosed because symptoms related hypersecretion. Clinically nonfunctioning do not produce specific syndromes, but often hypopituitarism results from insufficient secretion anterior hormones.