作者: Feifan Yu , Peter Järver , Per-Åke Nygren
DOI: 10.1371/JOURNAL.PONE.0056597
关键词: Chemistry 、 Immunoglobulin Fc Fragments 、 Protein domain 、 Immunoglobulin binding 、 Binding site 、 Antibody 、 Immunoglobulin G 、 Protein engineering 、 Biochemistry 、 Biotinylation
摘要: … engineering can be used to increase the interaction strength between the Z domain and Fc of mIgG 1 . … The resulting proteins were tested for binding to mIgG 1 and a preferred variant …