The pharmacology of basal forebrain involvement in cognition.
作者： James J. Chrobak , T. Celeste Napier , Israel Hanin , Thomas J. Walsh
DOI: 10.1007/978-1-4757-0145-6_22
关键词: Cholinergic 、 Mantle (mollusc) 、 Cholinergic neuron 、 Neurophysiology 、 Basal forebrain 、 Monoaminergic 、 Biology 、 Sensory processing 、 Nucleus basalis 、 Neuroscience
摘要: Magnocellular basal nucleus (MBN) neurons, a majority of which are cholinergic, directly influence cortical neurophysiology. These neurons appear to be part diffuse cortically projecting system that includes brain stem monoaminergic as well the MBN column. The entire appears modify excitability in relation an animal’s behavioral state (see Saper, 1987). By regulating activity within mantle, this can broad range cognitive phenomena (sensory processing, attention, motivation, memory). restrictive terminal distribution individual (Bigl et al., 1982: Price and Stern, 1983; Nyakas 1987) however, compared projections, may allow for more discrete modulation activity.
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