Mitochondria transfer enhances proliferation, migration, and osteogenic differentiation of bone marrow mesenchymal stem cell and promotes bone defect healing

作者: Yusi Guo , Xiaopei Chi , Yifan Wang , Boon Chin Heng , Yan Wei

DOI: 10.1186/S13287-020-01704-9

关键词: ChemistryMesenchymal stem cellMigration AssayTransplantationBone marrowCell biologyCellStem cellBone morphogenetic protein 2Alkaline phosphatase

摘要: Background Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is considered a promising therapeutic approach for bone defect repair. However, during the …

参考文章(50)
Ross E. B. Fitzsimmons, Matthew S. Mazurek, Agnes Soos, Craig A. Simmons, Mesenchymal Stromal/Stem Cells in Regenerative Medicine and Tissue Engineering. Stem Cells International. ,vol. 2018, pp. 8031718- ,(2018) , 10.1155/2018/8031718
Brianna H. Shares, Melanie Busch, Noelle White, Laura Shum, Roman A. Eliseev, Active mitochondria support osteogenic differentiation by stimulating β-catenin acetylation Journal of Biological Chemistry. ,vol. 293, pp. 16019- 16027 ,(2018) , 10.1074/JBC.RA118.004102
Sangho Roh, Huseyin Sumer, Jun Liu, Mesenchymal Stem Cells and Regenerative Medicine. Stem Cells International. ,vol. 2018, pp. 9810972- ,(2018) , 10.1155/2018/9810972
Svitlana Melnik, Nadine Werth, Stephane Boeuf, Eva-Maria Hahn, Tobias Gotterbarm, Martina Anton, Wiltrud Richter, Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells Stem Cell Research & Therapy. ,vol. 10, pp. 1- 18 ,(2019) , 10.1186/S13287-019-1187-Z
Heyangzi Li, Chao Wang, Teng He, Tengfei Zhao, Ying-ying Chen, Yue-liang Shen, Xiaoming Zhang, Lin-lin Wang, Mitochondrial Transfer from Bone Marrow Mesenchymal Stem Cells to Motor Neurons in Spinal Cord Injury Rats via Gap Junction. Theranostics. ,vol. 9, pp. 2017- 2035 ,(2019) , 10.7150/THNO.29400
Andrew J. Roger, Sergio A. Muñoz-Gómez, Ryoma Kamikawa, The Origin and Diversification of Mitochondria. Current Biology. ,vol. 27, ,(2017) , 10.1016/J.CUB.2017.09.015
Matthew R. Zanotelli, Zachary E. Goldblatt, Joseph P. Miller, Francois Bordeleau, Jiahe Li, Jacob A. VanderBurgh, Marsha C. Lampi, Michael R. King, Cynthia A. Reinhart-King, Regulation of ATP utilization during metastatic cell migration by collagen architecture. Molecular Biology of the Cell. ,vol. 29, pp. 1- 9 ,(2018) , 10.1091/MBC.E17-01-0041
Chenxia Hu, Lanjuan Li, None, Preconditioning influences mesenchymal stem cell properties in vitro and in vivo Journal of Cellular and Molecular Medicine. ,vol. 22, pp. 1428- 1442 ,(2018) , 10.1111/JCMM.13492
Hang Lin, Jihee Sohn, He Shen, Mark T. Langhans, Rocky S. Tuan, Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing Biomaterials. ,vol. 203, pp. 96- 110 ,(2019) , 10.1016/J.BIOMATERIALS.2018.06.026
Alan Trounson, Courtney McDonald, Stem Cell Therapies in Clinical Trials: Progress and Challenges Cell Stem Cell. ,vol. 17, pp. 11- 22 ,(2015) , 10.1016/J.STEM.2015.06.007