A novel numerical approach to stimulation of a specific brain region using transcranial focused ultrasound

摘要: One of the biggest challenges associated with transcranial application focused ultrasound is presence skull in wave propagation resulting attenuation and diffraction sound waves, which leads to disruption shifting acoustic focus brain. In this study, we were motivated find an optimal transducer position effectively deliver sufficient energy target brain whilst minimizing effects on a computationally inexpensive way. We hypothesized that placement single-element gives lowest reflection coefficient would be position. tested our hypothesis by conducting numerical investigations through targeting primary motor hand representation (M1) supplementary area (SMA). The positions determined using method (reflection coefficients lowest), whereby simulated magnitudes pressure values at M1 SMA respectively 91% 92% greater than those when greatest.