Constituents of Corynaea crassa "Peruvian Viagra"

作者: Gonzalo R. Malca Garcia , Lothar Hennig , Joachim Sieler , Rainer W. Bussmann

DOI: 10.1016/J.BJP.2015.02.007

关键词: Solid-stateTriterpeneStereochemistryLupeolBiologyKetoneBalanophoraceaePhytochemicalCorynaea crassa

摘要: A phytochemical investigation of methanol and n-hexane extracts tuber/roots Corynaea crassa Hook. f., Balanophoraceae, led to the isolation characterization β-sitosterol, lupenone, β-amyrone, lupeol, β-amyrine. Unusual complex 1:1 mixtures lupenone/β-amyrone lupeol/β-amyrine obtained from were identified by NMR HR-MS experiments. The structure mixture was confirmed X-ray analysis. These triterpene ketone derivatives, only distinguished either 5- or 6-membered E ring, co-crystallize in one common unit cell solid state.

参考文章(35)
Azhar I, Imam S, Hasan Mm, Ahmed Sw, Ali Ms, Two triterpenes lupanone and lupeol isolated and identified from Tamarindus indica linn. Pakistan Journal of Pharmaceutical Sciences. ,vol. 20, pp. 125- ,(2007)
Aldo Tinco, Jorge Arroyo, Pablo Bonilla, Efecto del extracto metanólico de Jatropha macrantha Müll. Arg., en la disfunción eréctil inducida en ratas Anales de la Facultad de Medicina. ,vol. 72, pp. 161- 168 ,(2013) , 10.15381/ANALES.V72I3.1061
Rainer W Bussmann, Glenn Ashley, Douglas Sharon, Gabriel Chait, Doris Diaz, Kamron Pourmand, Brian Jonat, Selma Somogy, Gladys Guardado, Cynthia Aguirre, Rosa Chan, Karen Meyer, Alyse Rothrock, Andrew Townesmith, Proving that Traditional Knowledge Works: The antibacterial activity of Northern Peruvian medicinal plants Ethnobotany Research and Applications. ,vol. 9, pp. 067- 096 ,(2011) , 10.17348/ERA.9.0.67-96
Rainer W Bussmann, Douglas Sharon, Traditional medicinal plant use in Northern Peru: tracking two thousand years of healing culture Journal of Ethnobiology and Ethnomedicine. ,vol. 2, pp. 47- 47 ,(2006) , 10.1186/1746-4269-2-47
Juan F Costa, J Tupac Otero, Marcela Mora, FIRST HOST RECORD FOR THE ROOT PARASITE CORYNAEA CRASSA (BALANOPHORACEAE) Acta Biológica Colombiana. ,vol. 14, pp. 197- 202 ,(2009)
D. Cremer, J. A. Pople, General definition of ring puckering coordinates Journal of the American Chemical Society. ,vol. 97, pp. 1354- 1358 ,(1975) , 10.1021/JA00839A011
Roshan C. Carpenter, Subramaniam Sotheeswaran, M. Uvais S. Sultanbawa, B. Ternai, 13C NMR studies of some lupane and taraxerane triterpenes Magnetic Resonance in Chemistry. ,vol. 14, pp. 462- 465 ,(1980) , 10.1002/MRC.1270140608
C. Desmarchelier, A. Gurni, G. Ciccia, A.M. Giulietti, Ritual and medicinal plants of the Ese'ejas of the Amazonian rainforest (Madre de Dios, Perú) Journal of Ethnopharmacology. ,vol. 52, pp. 45- 51 ,(1996) , 10.1016/0378-8741(96)01390-6