Dual innervation of the mammalian urinary bladder. A histochemical study of the distribution of cholinergic and adrenergic nerves.

摘要: The pattern of autonomic innervation the urinary bladder was studied in cat, dog, rabbit and rat, using specific histochemical technics for acetylcholinesterase norepinephrine. Cholinergic adrenergic ganglion cells exist all layers throughout wall. Large cholinergic nerve trunks coursing adventitial coat deep lamina propria branch into muscularis. terminal ramifications form a neuroterminal plexus which surrounds every smooth muscle cell fibers are less abundant, do not plexus, show regional variations number at different levels depths These suggest that two regions bladder, namely base body, may be distinguished on basis differences muscular innervation. In nerves grouped as superficial subepithelial nerves. latter networks variable complexity supply to epithelium. Throughout wall, blood vessels have dual perivascular from extend media. Although basic is similar species studied, certain relative abundance arrangement epithelial muscularis has uniform species.