Immuno‐PET: A Navigator in Monoclonal Antibody Development and Applications

作者: Guus A.M.S. van Dongen , Gerard W.M. Visser , Marjolijn N. Lub‐de Hooge , Elisabeth G. de Vries , Lars R. Perk

DOI: 10.1634/THEONCOLOGIST.12-12-1379

关键词: Positron emission tomographyMedical imagingMolecular imagingComputational biologyMedicineMonoclonal antibodyImmuno petPositron emittersMedical physicsRadioimmunotherapyPrimary breast cancerCancer researchOncology

摘要: … a powerful tool in cancer diagnosis, for the efficient selection and development of therapeutic antibodies, and for the selection of patients most likely to benefit from antibody therapy. …

参考文章(72)
Trastuzumab and breast cancer. The New England Journal of Medicine. ,vol. 345, pp. 995- 996 ,(2001) , 10.1056/NEJM200109273451312
Joseph S. Fruton, The Collected Papers of Paul Ehrlich. Yale Journal of Biology and Medicine. ,vol. 29, pp. 628- 628 ,(1957)
Eric O Aboagye, Frank Brady, Mathias Glaser, Pat Price, Veronica A Carroll, Henryk Barthel, Sajinder K Luthra, Roy Bicknell, David R Collingridge, Oliver C Hutchinson, Safiye Osman, Adrian L Harris, The development of [(124)I]iodinated-VG76e: a novel tracer for imaging vascular endothelial growth factor in vivo using positron emission tomography. Cancer Research. ,vol. 62, pp. 5912- 5919 ,(2002)
Darell D. Bigner, Michael R. Zalutsky, Ganesan Vaidyanathan, Fluorine-18-labeled monoclonal antibody fragments: a potential approach for combining radioimmunoscintigraphy and positron emission tomography. The Journal of Nuclear Medicine. ,vol. 33, pp. 1535- 1541 ,(1992)
Achim Magener, Jochen Schuhmacher, Uwe Haberkorn, Gabor Klivényi, Folker Amelung, Marcus Henze, Josef Doll, Sepp Kaul, Gunther Bastert, Hans Junkermann, Immunoscintigraphy with positron emission tomography: gallium-68 chelate imaging of breast cancer pretargeted with bispecific anti-MUC1/anti-Ga chelate antibodies Cancer Research. ,vol. 61, pp. 3712- 3717 ,(2001)
Jacek Koziorowski, Anna Lövqvist, John L. Humm, Keith S. Pentlow, Achim Jungbluth, Sydney Welt, Ron D. Finn, Shutian Ruan, Steven M. Larson, Arif Sheikh, Fook T. Lee, Martin W. Brechbiel, PET Imaging of 86Y-Labeled Anti-Lewis Y Monoclonal Antibodies in a Nude Mouse Model: Comparison Between 86Y and 111In Radiolabels The Journal of Nuclear Medicine. ,vol. 42, pp. 1281- 1287 ,(2001)
Thomas F. Budinger, Time-of-Flight Positron Emission Tomography: Status Relative to Conventional PET The Journal of Nuclear Medicine. ,vol. 24, pp. 73- 78 ,(1983)
E. Dijkers, M. N. Lub-de Hooge, J. G. Kosterink, P. L. Jager, A. H. Brouwers, L. R. Perk, G. A. van Dongen, E. G. de Vries, Characterization of 89Zr-trastuzumab for clinical HER2 immunoPET imaging Journal of Clinical Oncology. ,vol. 25, pp. 3508- 3508 ,(2007) , 10.1200/JCO.2007.25.18_SUPPL.3508
Cormac Sheridan, Pharma consolidates its grip on post-antibody landscape. Nature Biotechnology. ,vol. 25, pp. 365- 366 ,(2007) , 10.1038/NBT0407-365
Iris Verel, Gerard W. M. Visser, Maria J. W. D. Vosjan, Ronald Finn, Ronald Boellaard, Guus A. M. S. van Dongen, High-quality 124I-labelled monoclonal antibodies for use as PET scouting agents prior to 131I-radioimmunotherapy. European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 31, pp. 1645- 1652 ,(2004) , 10.1007/S00259-004-1632-8