Original Antigenic Sin in Ferrets: the Response to Sequential Infections with Influenza Viruses

摘要: Infection of ferrets with influenza viruses resulted in the production large numbers antibody molecules low avidity. With passage time number decreased while average avidity increased. Sequential infection serologically related caused a marked increase reacting first virus. The this was similar to that before reinfection. second virus secondary quality. population 18 21 days after heterogeneous terms avidity, some antibodies either one or other infecting and both viruses.