Ascites in Ibadan, Nigeria- usefulness of albumin gradient in its etiologic diagnosis

作者: U. H. Malabu , I. O. Olubuyide , M. E. Shaibu , F. Olawuyi

DOI:

关键词: PopulationInternal medicineDifferential diagnosisAscitesGastroenterologyCirrhosisAscitic fluidPathologyNephrotic syndromeAlbuminMedicineProspective cohort study

摘要: In a 2-year prospective study, ninety adult patients with ascites at the University College Hospital Ibadan were evaluated clinically in addition to diagnostic work-up protocol. Of these, 40 (44%) had liver cirrhosis, 21 (23%) tuberculous peritonitis, 20 (22%) ma-lignant ascites, 5 (6%) heart diseases and 4 (5%) nephrotic syndrome. Albumin gradient was compared usual parameters of ascitic fluid analysis differential diagnosis ascites. We showed that total protein concentration, fluid/serum protein, lactic dehydrogenase, dehydrogenase lower cirrhosis than peritonitis (p 180 IU/L (77%), >3.0 g/dL (73%), serum dehydro-genase ratio >0.6 (70%) >0.5 (63%). It is concluded malignancies are commonest causes Ibadan. While this study shows albumin best diag-nostic discrimination between caused by due or malignant tumors, further studies on larger population environment however indicated.

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