THREE-DIMENSIONAL IN SITU TEMPERATURE MEASUREMENT IN MICROFLUIDIC SYSTEM USING BROWNIAN MOTION OF NANOPARTICLES
作者： Victor Breedveld , Kwanghun Chung , Hang Lu , Jaekyu Cho , Lauren Cheplen
DOI:
关键词: Microfluidics 、 Nanoparticle 、 In situ 、 Thermal diffusivity 、 Brownian motion 、 Temperature measurement 、 Reproducibility 、 Tracking (particle physics) 、 Biological system 、 Materials science
摘要: We report an in situ method for temperature measurement microfluidic systems using Brownian diffussion of nanoparticles. This is superior its reproducibility and reduced systematic errors as measuring diffusivity does not rely on fluorescence intensity or lifetime fluorophores. Threedimensional mapping was achieved a simple videomicroscopy setup combination with software analysis that enables selective tracking In addition, we successfully demonstrated the capability this noninvasive tool biological samples.
elsevier.com
rsc.org 参考文章(4)
David Ross, Michael Gaitan, Laurie E. Locascio, Temperature measurement in microfluidic systems using a temperature-dependent fluorescent dye. Analytical Chemistry. ,vol. 73, pp. 4117- 4123 ,(2001) , 10.1021/AC010370L
V Hohreiter, S T Wereley, M G Olsen, J N Chung, Cross-correlation analysis for temperature measurement Measurement Science and Technology. ,vol. 13, pp. 1072- 1078 ,(2002) , 10.1088/0957-0233/13/7/314
Elena M. Lucchetta, Ji Hwan Lee, Lydia A. Fu, Nipam H. Patel, Rustem F. Ismagilov, Dynamics of Drosophila embryonic patterning network perturbed in space and time using microfluidics Nature. ,vol. 434, pp. 1134- 1138 ,(2005) , 10.1038/NATURE03509
Urban Seger-Sauli, Marilia Panayiotou, Silvan Schnydrig, Martin Jordan, Philippe Renaud, Temperature measurements in microfluidic systems: Heat dissipation of negative dielectrophoresis barriers Electrophoresis. ,vol. 26, pp. 2239- 2246 ,(2005) , 10.1002/ELPS.200410358