Prise en charge des proliférations épithéliales du sein avec et sans atypies : hyperplasie canalaire atypique, métaplasie cylindrique avec atypie, néoplasies lobulaires, proliférations épithéliales sans atypie, mastopathie fibrokystique, adénose, cicatrices radiaires, mucocèles, lésions prolifératives apocrines : recommandations pour la pratique clinique

摘要: In the last few years, diagnostics of high-risk breast lesions (atypical ductal hyperplasia [ADH], flat epithelial atypia [FEA], lobular neoplasia: atypical [ALH], carcinoma in situ [LCIS], radial scar [RS], usual [UDH], adenosis, sclerosing adenosis [SA], papillary lesions, mucocele-like lesion [MLL]) have increased with growing number percutaneous biopsies. The management these is highly conditioned by enlarged risk cancer combined either an probability finding after surgery, a possible malignant transformation (in or invasive cancer), developing on long range. An overview literature reports grade C recommendations concerning and follow-up lesions: case ADH, FEA, ALH, LCIS, RS, MLL atypia, diagnosed biopsies: surgical excision recommended; diagnostic based vacuum-assisted core biopsy complete disappearance radiological signal for FEA RS without atypia: abstention valid alternative approved multidisciplinary meeting. ALH (incidental finding) associated benign responsible signal: may be proposed; UDH, concordance radiology histopathology findings must ensured. No data available to recommend surgery; non-in sano resection LCIS (except pleomorphic type), MLL: surgery does not seem necessary; previous LCIS: specific recommended accordance HAS's recommendations. little are yet differ from others atypia; fibro cystic disease: no agreement