Pyruvate formate-lyase activating enzyme: elucidation of a novel mechanism for glycyl radical formation.
作者： Jeffrey M. Buis , Joan B. Broderick
DOI: 10.1016/J.ABB.2004.09.028
关键词: Chemistry 、 Active site 、 Sulfonium 、 Homolysis 、 Iron–sulfur cluster 、 Stereochemistry 、 Binding site 、 Photochemistry 、 Electron transfer 、 Cluster (physics) 、 Radical SAM
摘要: … Pyruvate formate lyase activating enzyme is a member of a novel superfamily of enzymes … Work in our laboratory on pyruvate formate lyase activating enzyme is supported by a grant …
montana.edu
elsevier.com
sci-hub.se 参考文章(54)
Edwin Constable, Comprehensive coordination chemistry II : from biology to nanotechnology Elsevier. ,(2004)
M. Frey, M. Rothe, A.F. Wagner, J. Knappe, Adenosylmethionine-dependent synthesis of the glycyl radical in pyruvate formate-lyase by abstraction of the glycine C-2 pro-S hydrogen atom. Studies of [2H]glycine-substituted enzyme and peptides homologous to the glycine 734 site. Journal of Biological Chemistry. ,vol. 269, pp. 12432- 12437 ,(1994) , 10.1016/S0021-9258(18)99892-3
M Moss, P A Frey, The role of S-adenosylmethionine in the lysine 2,3-aminomutase reaction. Journal of Biological Chemistry. ,vol. 262, pp. 14859- 14862 ,(1987) , 10.1016/S0021-9258(18)48103-3
J Baraniak, M L Moss, P A Frey, Lysine 2,3-aminomutase. Support for a mechanism of hydrogen transfer involving S-adenosylmethionine. Journal of Biological Chemistry. ,vol. 264, pp. 1357- 1360 ,(1989) , 10.1016/S0021-9258(18)94194-3
Volker UNKRIG, Franz A. NEUGEBAUER, Joachim KNAPPE, The free radical of pyruvate formate-lyase: characterization by EPR spectroscopy and involvement in catalysis as studied with the substrate-analogue hypophosphite FEBS Journal. ,vol. 184, pp. 723- 728 ,(1989) , 10.1111/J.1432-1033.1989.TB15072.X
Louis Noodleman, David A. Case, Density-Functional Theory of Spin Polarization and Spin Coupling in Iron—Sulfur Clusters Advances in Inorganic Chemistry. ,vol. 38, pp. 423- 470 ,(1992) , 10.1016/S0898-8838(08)60070-7
T.P. Chirpich, V. Zappia, R.N. Costilow, H.A. Barker, Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme. Journal of Biological Chemistry. ,vol. 245, pp. 1778- 1789 ,(1970) , 10.1016/S0021-9258(19)77160-9
Perry A. Frey, Lysine 2,3-aminomutase: is adenosylmethionine a poor man's adenosylcobalamin? The FASEB Journal. ,vol. 7, pp. 662- 670 ,(1993) , 10.1096/FASEBJ.7.8.8500691
Wolfgang Kabsch, Joachim Knappe, Andreas Becker, Karin Fritz-Wolf, Sabine Schultz, A. F. Volker Wagner, Structure and mechanism of the glycyl radical enzyme pyruvate formate-lyase Nature Structural & Molecular Biology. ,vol. 6, pp. 969- 975 ,(1999) , 10.1038/13341
Roberto Rebeil, Yubo Sun, Lilian Chooback, Mario Pedraza-Reyes, Cynthia Kinsland, Tadhg P. Begley, Wayne L. Nicholson, Spore Photoproduct Lyase from Bacillus subtilis Spores Is a Novel Iron-Sulfur DNA Repair Enzyme Which Shares Features with Proteins such as Class III Anaerobic Ribonucleotide Reductases and Pyruvate-Formate Lyases Journal of Bacteriology. ,vol. 180, pp. 4879- 4885 ,(1998) , 10.1128/JB.180.18.4879-4885.1998