Covalent dimerization of vascular permeability factor/vascular endothelial growth factor is essential for its biological activity. Evidence from Cys to Ser mutations.
作者： A J Pötgens , N H Lubsen , M C van Altena , R Vermeulen , A Bakker
DOI: 10.1016/S0021-9258(20)30073-9
关键词: Vascular endothelial growth factor A 、 Mutant 、 Growth factor 、 Cysteine 、 Serine 、 Biochemistry 、 Biology 、 Biological activity 、 Platelet-derived growth factor receptor 、 Cysteine metabolism
摘要: … factor in the regulation of vascular growth and vascular permeability. … cysteine residues conserved with platelet-derived growth factor (PDGF). To study the role of some of these cysteine …
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