TLR7, IFNγ, and T-bet: their roles in the development of ABCs in female-biased autoimmunity.
作者： Kira Rubtsova , Philippa Marrack , Anatoly V. Rubtsov
DOI: 10.1016/J.CELLIMM.2014.12.002
关键词: Sex characteristics 、 Biology 、 X chromosome 、 TLR7 、 Interferon gamma 、 Gut flora 、 Immune system 、 Genetics 、 Autoimmunity 、 Immunology 、 Receptor
摘要: The majority of autoimmune diseases have a strong gender bias, affecting mostly females. Gender-specific factors like sex-hormones, the presence or absence of a second X …
elsevier.com
sci-hub.se 参考文章(48)
C Haas, B Ryffel, M Le Hir, IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice. Journal of Immunology. ,vol. 158, pp. 5484- 5491 ,(1997)
Argyrios N Theofilopoulos, Stefanos Koundouris, Dwight H Kono, Brian R Lawson, The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity. Arthritis Research & Therapy. ,vol. 3, pp. 136- 141 ,(2001) , 10.1186/AR290
R Hal Scofield, Gail R Bruner, Bahram Namjou, Robert P Kimberly, Rosalind Ramsey‐Goldman, Michelle Petri, John D Reveille, Graciela S Alarcón, Luis M Vilá, Jeff Reid, Bryan Harris, Shibo Li, Jennifer A Kelly, John B Harley, None, Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: Support for the notion of a gene‐dose effect from the X chromosome Arthritis & Rheumatism. ,vol. 58, pp. 2511- 2517 ,(2008) , 10.1002/ART.23701
Grant C. Hughes, Divaker Choubey, Modulation of autoimmune rheumatic diseases by oestrogen and progesterone Nature Reviews Rheumatology. ,vol. 10, pp. 740- 751 ,(2014) , 10.1038/NRRHEUM.2014.144
Eleanor N. Fish, The X-files in immunity: sex-based differences predispose immune responses. Nature Reviews Immunology. ,vol. 8, pp. 737- 744 ,(2008) , 10.1038/NRI2394
Anatoly V. Rubtsov, Kira Rubtsova, Aryeh Fischer, Richard T. Meehan, Joann Z. Gillis, John W. Kappler, Philippa Marrack, Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity Blood. ,vol. 118, pp. 1305- 1315 ,(2011) , 10.1182/BLOOD-2011-01-331462
Clara M Pelfrey, Anne C Cotleur, Jar-Chi Lee, Richard A Rudick, Sex differences in cytokine responses to myelin peptides in multiple sclerosis Journal of Neuroimmunology. ,vol. 130, pp. 211- 223 ,(2002) , 10.1016/S0165-5728(02)00224-2
Pheh-Ping Chang, Giles Walters, Carola G. Vinuesa, Sau K. Lee, Diego G. Silva, Jaime L. Martin, Alvin Pratama, Xin Hu, Interferon-γ Excess Leads to Pathogenic Accumulation of Follicular Helper T Cells and Germinal Centers Immunity. ,vol. 37, pp. 880- 892 ,(2012) , 10.1016/J.IMMUNI.2012.10.010
Anatoly V. Rubtsov, Kira Rubtsova, John W. Kappler, Philippa Marrack, TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunologic Research. ,vol. 55, pp. 210- 216 ,(2013) , 10.1007/S12026-012-8365-8
J. Mossong, C.J. O’Callaghan, S. Ratnam, Modelling antibody response to measles vaccine and subsequent waning of immunity in a low exposure population. Vaccine. ,vol. 19, pp. 523- 529 ,(2000) , 10.1016/S0264-410X(00)00175-4